ALKBH5 and leukemia: For example, two ALKBH5 inhibitors, 2-{[1-hydroxy-2-oxo-2-phenylethyl] sulfanyl}acetic acid and 4-{[furan-2-yl]methyl}amino-1,2-diazinane-3,6-dione, can effectively inhibit the proliferation of leukemia cells (HL-60, CCRF-CEM, and K562) at low micromolar concentrations (138).