Among these, 17 were identified as differentially expressed SLE associated genes (DEAGs), including AGPAT4, BCAR3, CD4, DDR2, F11R, FARP1, FCGR2A, FRMPD1, HECW2, ITGA11, MCTP2, NUDCD3, PPIF, RASA3, SUMF1, TMEM181, and USP8 (Table S6). Here, HECW2 is linked to systemic lupus erythematosus.