USP8 and systemic lupus erythematosus: Among these, 17 were identified as differentially expressed SLE associated genes (DEAGs), including AGPAT4, BCAR3, CD4, DDR2, F11R, FARP1, FCGR2A, FRMPD1, HECW2, ITGA11, MCTP2, NUDCD3, PPIF, RASA3, SUMF1, TMEM181, and USP8 (Table S6).