TNF-α plays a key role in mediating pulmonary inflammation and exacerbating lung injury.[30] CRP, an acute-phase protein produced by the liver, is a vital biomarker for diagnosing pediatric pneumonia.[31] PCT serves as a specific indicator for bacterial infection, with elevated levels indicating more severe Mycoplasma pneumoniae infection.[32] Therefore, the observed reductions suggest that XFG may alleviate pulmonary inflammatory damage, potentially through inhibitory effects on Mycoplasma pneumoniae. The gene discussed is TNF; the disease is bacterial infectious disease.