PTPRC and hyperlipidemia: Myeloid cells (granulocytes, monocytes, macrophages, and DCs) are innate immune guards against infections and become the protagonists of cardiovascular disease in the context of hyperlipidemia, most of which are generated by hematopoietic stem cells (HSCs).[88] Our findings suggest that hematopoietic stem cell absolute count and CD45 on lymphocyte are associated with MI in myeloid cells panel, where hematopoietic stem cell absolute count increase the risk of MI, whereas CD45 on lymphocyte decreases the risk of MI.