However, it has since been noted that individuals with CD40 deficiency always have concomitant T-cell and dendritic cell dysfunction.[82] By comparing CD40 expression in patients with stable angina to patients with AMI was significantly decreased in the AMI group, suggesting that there may be immune system dysfunction in patients with AMI.[83] It may account for the conclusions of the present experiment. This evidence concerns the gene CD40 and angina pectoris.