Studies only shown that basophils have a reparative effect on the infarcted myocardium after MI via the secretion of IL-4/IL-13,[73–75] but more recent studies have shown that monocyte-derived macrophages and other leukocytes, such as DCs, mast cells, B cells, T-cells, NK-cells, and Treg-cells, also play an important role in the healing of MI. This evidence concerns the gene IL4 and myocardial infarction.