The investigation of the differential apoptotic mechanisms of CD16+ and CD16− monocyte subpopulations in homeostatic and infected states has contributed to an in-depth comprehension of the regulatory role of these subpopulations under RA pathological conditions.[39] One study analyzed the immunophenotypic and transcriptomic characteristics of CD14+ monocytes in the bone marrow of patients with multiple myeloma. The gene discussed is CD14; the disease is rheumatoid arthritis.