HMGCR and neuroblastoma: We further analyzed the expression of the rate-limiting key enzyme in each pathway (GPX4 for the glutathione pathway, HMG-CoA reductase [encoded by HMGCR] for the mevalonate pathway, and TrxR [encoded by TXNRD1] for the thioredoxin pathway) in another single-nuclei dataset comprised of 22 NB patient tumors32.