Evaluating the prevalence of the SLC26A4 gene variants in our cohort of 32 Sudanese families with CH comprising 72 individuals, irrespective of their gender and age, we report that 56.3% families and 45.8% individuals are harboring SLC26A4 variants, most of them being heterozygous (Table 2; Fig. 2). This evidence concerns the gene SLC26A4 and cyclic hematopoiesis.