CCK8 assay, soft agar clone formation assay, and transwell assays showed that HCAR1 overexpression enhanced the proliferation, tumor spheres, migratory, and invasive capabilities of MG‐63 and 143‐B cells, whereas HCAR1 knockdown substantially reduced these properties in both cell lines (Figure 2H–O; Figure S3H,I, Supporting Information). The gene discussed is HCAR1; the disease is neoplasm.