PTPA and pancreatic neoplasm: For instance, inhibition of PP2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair;[52] PP2A dephosphorylates p38 enhances endothelial cell survival under stress condition.[53] These findings demonstrate that the role of PP2A as either tumor‐suppressive or pro‐tumorigenic is not absolute but is context‐dependent, varying according to tumor type and the specific molecular targets it regulates.