Asthma duration, yr., median (IQR): 27.5 (13.5, 46.1). % patients requiring OCS burst/s for exacerbations (past yr): 97.3. Pre‐BD FEV1% pred.: 57.0 (17.9). Post‐BD FEV1% pred.: 62.8 (19.0). ACT score, median (IQR): 11.0 (9.0, 15.0). BEC (cells/mL), median (IQR): 590.0 (400.0, 830.0). IgE (IU/mL), median (IQR): 141.5 (54.0, 461.5). FeNO (ppb), median (IQR): 35.0 (20.0, 61.0). OCS dose, (mg/day), median (IQR): 10.0 (5.0, 12.5) The gene discussed is IGHE; the disease is asthma.