During typical neurodevelopment, the refinement of functional connectivity among brain regions supports the emergence of CF; however, abnormalities in this process—either in the form of excessive variability or weakened integration—are associated with CF dysfunction, as seen in neurodevelopmental disorders such as autism spectrum disorder (ASD) and neurodegenerative conditions like Alzheimer's disease (AD) [11]. Here, CFTR is linked to Alzheimer disease.