Using the pathway analysis tool Enrichr (38), we identified DPT-upregulated pathways in tumor cells (pluripotency, mRNA processing, nuclear receptors, and ErbB signaling) as well as markedly downregulated pathways in immune activation–related phagocytosis; IL-3, IL-5, and IL-1 signaling; and chemokine signaling (Figure 3G and Supplemental Table 4). This evidence concerns the gene IL3 and neoplasm.