These data were supported by IHC staining findings in intradermally injected allograft primary tumors borne by aged mice (>52 weeks old) that expressed higher levels of NR2F1 compared with tumors in young mice (8 weeks old) (Figure 6B and Supplemental Figure 6); tumor sizes exceeded approximately 500 mm3 in size in young and aged mice (8). The gene discussed is NR2F1; the disease is neoplasm.