SARM1 and neuroblastoma: However, when we silenced SARM1 in the Neuro2a neuroblastoma cell line, which undergoes lower NAD depletion kinetics compared to SH‐SY5Y cells after Vacor exposure (Fig. 5E), we found that silencing (Fig. 5F) completely prevented Vacor‐dependent NAD depletion (Fig. 5G).