In patients with GT-3, factors such as female gender, absence of cirrhosis, young age, and low initial viral load were identified as predictors of SVR.17 In the study in Poland with real-life data, male sex, liver cirrhosis, BMI ≥ 25 kg/m2, infection with GT-3, presence of esophageal varices, concomitant diabetes, receiving previous ineffective treatment, baseline ALT activity >70 U/L, higher bilirubin concentration, and lower albumin level and platelet count were negative predictors of an SVR.18 This evidence concerns the gene GPT and esophageal varices.