Abdominal pain; ascites; dark urine; epistaxis; family history of liver disease; fatty infiltration, contour irregularity associated with cirrhosis and regenerative nodules; fever; grade I–IV on West Haven Classification for hepatic encephalopathy; gynaecomastia; hemolytic anemia with (–) direct Coombs test; hepatosplenomegaly; high AST/ALT ratio; jaundice; low ALP, low ALP ratio; nausea, vomiting; peripheral edema; portal hypertension; pruritus; right-lobe atrophy on ultrasound. The gene discussed is GPT; the disease is Hepatosplenomegaly.