CV: cardiovascular; HHF: hospitalization for heart failure; MI: myocardial infarction; LVEDV: left ventricular end-diastolic volume; LVESV: left ventricular end-systolic volume; NT-proBNP: N-terminal pro-B-type natriuretic peptide; QoL: quality of life; NS: not significant. This evidence concerns the gene NPPB and heart failure.