His liver function test revealed a predominantly direct hyperbilirubinemia (total bilirubin of 32 mmol/l with a direct bilirubin of 28 mmol/l), elevated serum alanine transaminases (alanine aminotransferase (ALT) of 566 U/l, aspartate aminotransferase (AST) of 478 IU/l) and serum alkaline phosphatase of 181 U/l. The gene discussed is GPT; the disease is Hyperbilirubinemia.