OSR1 and Hepatic fibrosis: Wt1+ fibroblasts displayed distinct expression of genes, such as Scara5, Fbln2, Adgrd1, and Osr1 (encoding the odd-skipped related transcription factor 1) that has been linked to liver fibrosis (Nian et al, 2024), and mesenchymal collagen production (Murugapoopathy et al, 2021) (Fig. EV3E).