RIPK1 and Sepsis: Studies have shown that RIPK1, a necroptosis‐associated protein, is continuously elevated in the plasma of patients with severe COVID‐19 driven by cytokine storms.[14] Our clinical analysis of sepsis patients demonstrated that plasma P‐RIPK1 levels positively correlated with Sequential Organ Failure Assessment (SOFA) scores (Figure1A) and inversely correlated with the PaO2/FiO2 ratio (Figure 1B), suggesting its prognostic utility for systemic organ dysfunction and hypoxemic respiratory failure.