Selenoprotein T (SELENOT) is a 22 kDa membrane‐associated selenoprotein that inhibits oxidative stress and maintains intracellular homeostasis.[23] Most studies on SELENOT have focused on its role in cardiovascular disease, confirming its influence on cell structure and adhesion properties.[24] The muscle‐related functions of selenoproteins (SELENOW, GPx3, and GPx4) are well‐understood; however, the function of SELENOT in skeletal muscles, especially in muscle atrophy, has been less studied. This evidence concerns the gene SELENOT and cardiovascular disorder.