WNT7B and neoplasm: In a third model, GL-261-MGH cell line, the mRNA expression of Wnt ligands was 200 to 500-fold lower than in 005GSC cell line; and Wnt7b protein level was ~10-fold lower in GL-261-MGH tumor tissue than in 005GSC tumor tissue (SI Appendix, Fig. S3 B and C).