PTEN and ovarian cancer: Significant deletions were observed in regions such as 5q11-13, frequently reported as loss of heterozygosity (LOH) in ovarian cancer [15], 8p23 encoding DBC1 (deleted in breast cancer 1 gene), 10p24 harboring PTEN, 16q24 encoding CDH1 (E-cadherin) and FANCA, and 19q13.3 encompassing STK11 (LKB1).