Of 116 women who were aged 60 years and older, 16 (13.7%) were found to have a P/LP mutation of BRCA1 and BRCA2. The prevalence of BRCA1 and BRCA2 P/LP of 4.8% reported in our series of 2401 patients is comparable to what has been reported in other reports of universal genetic testing in women with breast cancer.9,10. The gene discussed is BRCA2; the disease is breast carcinoma.