Among the identified interactors, LRP6, a coreceptor in the Wnt signalling pathway, CTNNB1 (β‐catenin), and CTNND1 (p120‐catenin) represent pivotal components of Wnt and cadherin‐mediated adhesion signaling, both of which are frequently dysregulated in pancreatic cancer, thereby contributing to augmented cell proliferation and metastatic potential (Aguilera and Dawson 2021; Xue et al. 2024). This evidence concerns the gene LRP6 and familial pancreatic carcinoma.