Vaidya and Collogues, for instance, studied the Differentiation Antagonizing Non-Coding RNA (DANCR), which is a non-coding RNA involved in the regulation of different oncogenic mechanisms and undruggable by conventional molecules; it was demonstrated that the delivery of siRNA against DANCR and its subsequent inhibition epigenetically represses the expression of cancer-driven pathways, such as Wnt signaling, EMT, and phosphorylation of several kinases: siDANCR-NP effectively inhibits migration and invasion of cancer cells in vitro and tumor growth in vivo (63). The gene discussed is DANCR; the disease is cancer.