In summary, this prediction model holds significant clinical value with three key implications: First, the VO2peak and METsmax prediction equations incorporating six routinely available clinical parameters (sex, BMI, NT-proBNP, glucose, 6MWD, and SBP) enable rapid outpatient assessment of CRF in AF patients following RFCA, which will provide objective data to guide clinical decision-making. Here, NPPB is linked to atrial fibrillation.