Our research indicates that diabetes influences this process (3.50 ± 0.52 mm vs. 4.78 ± 0.55 mm, p < 0.001), and it is achieved by inhibiting the expression of osteoclast-related factors RANK, RANKL, and OPN, which affects the growth and development of osteoclasts and promotes the absorption of the alveolar bone (p < 0.05). The gene discussed is SPP1; the disease is diabetes mellitus.