TG and hypothyroidism: The above, combined with the third of respondents who agreed with the statement that “It’s safe to be slightly over-treated with thyroid hormones (e.g. having a TSH below the normal range)”, are relevant to the concerning trend noted of a falling serum TSH threshold for initiation of treatment for hypothyroidism and the rising number of euthyroid people treated with TH (2, 42, 43).