FLT3 and acute myeloid leukemia: The significance of FLT3-ITD indicates prognosis and alters treatment approaches, making it a mutational test for classifying AML subtypes according to the World Health Organization’s definition of the disease in 2022 (WHO classification of hematolymphoid tumors, 5th edition: Myeloid and Histiocytic/Dendritic neoplasms) (6).