SLC7A1 and colorectal carcinoma: In CRC cells, L-arginine uptake is mediated by the upregulated transporters Solute Carrier Family 7 Member 1 (SLC7A1),also known as Cationic Amino Acid Transporter 1 (CAT-1) and Solute Carrier Family 6 Member 14 (SLC6A14).