BV, on the other hand, contains melittin and phospholipase A2, which disrupt cancer cell membranes, enhance cellular permeability, and initiate apoptotic signaling through activation of the p53 pathway and inhibition of PI3K/AKT/mTOR and NF-κB survival pathways (25, 26, 31–35). The gene discussed is MTOR; the disease is cancer.