NMOSD: neuromyelitis optica spectrum disorder; MOGAD: myelin oligodendrocyte glycoprotein antibody-associated disease; IV MPS: intravenous methylprednisolone; IVIG: intravenous immunoglobulin; PLEX: plasma exchange; MMF: mycophenolate mofetil. The gene discussed is OMG; the disease is neuromyelitis optica.