This was confirmed by Cao et al. who found that LncRNA-BTX is upregulated by IRF3 -type I interferon-independent pathway after viral infection to help the virus evade clearance by the immune system, and also regulates the intracellular localisation of DHX9 and ILF3 by enhancing the interactions of RNA-binding proteins (RBPs) DHX9 and ILF3 with their partner proteins (JMJD6 and ILF2). This evidence concerns the gene DHX9 and viral infectious disease.