Six LRRK2 p.A419V carriers also carried a concomitant p.G2385R variant (mean AAO: 51.3 ± 13 years), and one patient with young onset, unknown monogenic PD status (AAO: 35 years) was found to have a concomitant p.R1628P variant (Supplementary Table 8). This evidence concerns the gene LRRK2 and Parkinson disease.