These include Shwachman-Diamond syndrome affecting neutrophils, caused by a mutated ribosome biogenesis factor 36, Diamond Blackfan Anemia caused by mutations in ~20 ribosomal proteins that causes selective defects in erythroid progenitors 38, specific thrombocytopenia caused by mutation in SLFN14 that causes defects in rRNA regulation which affects platelets 33. The gene discussed is SLFN14; the disease is Diamond-Blackfan anemia.