IL1B and infection: In contrast, iMg failed to secrete any of these pro-inflammatory molecules at significant rates following infection with HIV at either the protein or the mRNA level (Figure 1d, 1e), with the exception of IL-1β, which was observed only at the transcript level(Figure 1e) indicating that mature IL-1β cleavage and secretion was not occurring in HIV-infected iMg monocultures, indicating reduced canonical anti-viral and pro-inflammatory immune responses in iMg compared to MDMs.