Using cells from this resource, we examined the effects on gene expression and pre-mRNA splicing patterns caused by common familial PD mutations in the PRKN, SNCA, LRRK2, PINK1, DNAJC6, FBXO7, SYNJ1, PARK7, VPS13C, ATP13A2 and GBA1 genes (Kruger et al., 1998, Polymeropoulos et al., 1997, Isaacs et al., 2017, Sasaki et al., 2004). Here, SNCA is linked to Parkinson disease.