DOCK3 and Ataxia: DOCK3 dysregulation has been shown to be associated with neurodegenerative disorders, including neurodevelopmental disorders with impaired intellectual development, hypotonia, and ataxia (Alexander and Velinov, 2023, Iwata-Otsubo et al., 2018, Wiltrout et al., 2019, Namekata et al., 2010).