CCL2 and neoplasm: Building upon this strategy, Zhao et al. (2018) introduced a biomimetic approach by cloaking hollow bismuth selenide nanoparticles with macrophage membranes and loading them with quercetin (a known heat shock protein inhibitor).80 The resulting M@BS-QE nanoparticles exhibited enhanced immune evasion and prolonged systemic circulation due to the macrophage-derived membrane, which facilitated tumor accumulation via CCL2-mediated recruitment and active homing.