CD47 and neoplasm: Guo et al. (2019) laid the foundation by demonstrating the multifunctional utility of CD47-targeted bismuth selenide nanoparticles (Ab-PEG-Bi2Se3) in augmenting photothermal therapy (PTT).102 While not a direct RT-CDT study, this work revealed the versatility of BiNPs in tumor immunomodulation through enhanced macrophage-mediated phagocytosis, which supports immune-mediated cytotoxicity synergistic with physical treatment modalities.