Increase in soluble GFAP following ischemic stroke has been an independent indicator of clinical outcomes and rehabilitation measured by National Institutes of Health Stroke Scale (NIHSS) following acute ischemic stroke, Trunk Control Test (TCT), Functional Ambulation Classification (FAC), and Functional Independence Measure (FIM) scores 3 months following the acute ischemic stroke[64]. Here, GFAP is linked to Stroke.