Another review conducted in adults with overweight or obesity, but that performed a meta-analysis, showed similar effects of DF intake on circulating CRP concentrations, showing a significant reduction in this inflammatory marker compared to the C group (–0.37 mg/L; (95% CI: –0.74, 0 mg/L) [32]. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.