GLP1R and hyperthyroidism: Although liraglutide-induced hyperthyroidism is not widely reported, thyroid dysfunction has been observed in the context of GLP-1 RA use.8,9 Preclinical studies in rodents have highlighted a potential link between GLP-1 RAs and thyroid C-cell pathology, although these findings have not been conclusively replicated in humans.2 It is important to note the possible species-specific effects of GLP-1 RAs on thyroid hormones; therefore, caution should be exercised when extrapolating the same result to humans.