Other co-existing genetic alterations associated with tumor progression and shorter survival in oligodendroglioma include homozygous PIK3CA mutation (Broderick et al., 2004; Tateishi et al., 2019), TCF12 mutation (Labreche et al., 2015) and increased MYC signaling (Kamoun et al., 2016). The gene discussed is TCF12; the disease is neoplasm.