TNFSF12-TNFRSF12A, TGFB2-(TGFBR1+TGFBR2), TGFB2-(ACVR1B + TGFBR2), TGFB2-(ACVR1+TGFBR1), PSAP-GPR37, MIF- (CD74+CXCR4), MIF-(CD74+CXCR2), MIF-(CD74+CD44), CXCL12-CXCR4, and BMP4-(BMPR1B + BMPR2) were secreted LR pairs specifically involved in MF2 cells communication with hepatocytes in HCC patients with MVI present (Figures 3C,D). Here, ACVR1 is linked to hepatocellular carcinoma.