MiR-532-5p alleviates depression-like behaviors in CUMS-exposed mice by suppressing the expression of IL-6, interleukin-1 beta (IL-1β), TNF-α, and monocyte chemoattractant protein-1 through inhibition of the signal transducer and activator of transcription 3 pathway (Yan et al., 2020). This evidence concerns the gene IL1B and major depressive disorder.