In addition, WT mice showed no changes in p-JNK levels (Thr183/Tyr185) (Student’s two-tailed t-test, p > 0.05, n ≥ 4; Figures 9A–C), while in AD mice, the prefrontal cortex, cortex, and midbrain showed about twofold upregulation in p-JNK (Student’s two-tailed t-test, p < 0.001, n ≥ 4; Figures 9D–F). The gene discussed is MAPK8; the disease is Alzheimer disease.