GRIN2A and Alzheimer disease: GluN2A subunit expression showed significant increase with aging in WT and AD mice across most brain regions (hippo: ANOVA, p = 0.010, F (1, 12) = 8.18; pfc: ANOVA, p = 0.010, F (1, 12) = 8.21; ctx: ANOVA, p = 0.020, F (1, 12) = 6.01, n ≥ 4; Figures 2A,B), except in the midbrain which only showed significant increase in aged WT mice (mb: ANOVA, p = 0.030, F (1, 12) = 5.50, n ≥ 4; Figures 2A,B).