KLRK1 and neoplasm: Upregulation of NKG2D on senescent cells was targetable with NKG2D CAR-T cells which induced cytotoxic responses to eliminate senescent cells in age-associated diseasesNKG2D-CAR-T cells exhibit superior tumor infiltration, persistence, and cytotoxicity compared to CD19-CAR-T cellsGreater tolerability and lower treatment-associated toxicities