S100A8 and myocardial infarction: Also, S100A8/A9 was independently associated with recurrent myocardial infarction or cardiovascular death in a subgroup analysis of patients enrolled in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE-IT TIMI 22 trial), suggesting the multifaced role of this heterodimer (55).