NPPB and atrial fibrillation: 1. A high prevalence of CMD (75%) was found in patients with HFpEF.2. Worse CFR was significantly associated with higher NT-proBNP, higher urinary albumin-to-creatinine ratio (UACR), lower RHI, and right ventricular (RV) dysfunction.3. History of smoking and atrial fibrillation were the comorbidities most closely associated with CMD.