Among these, lncRNAs, such as Fetal lethal non-coding developmental regulatory RNA (FENDRR) (8), ZNFX1 antisense RNA 1 (ZFAS1) (9), and nuclear paraspeckle assembly transcript 1 (NEAT1) (10) have been found to participate in a variety of pathophysiological processes, including AMI and heart failure (HF). The gene discussed is NEAT1; the disease is heart failure.