Recent bioinformatic analyses have identified a set of ferroptosis- and autophagy-related genes, including Prostaglandin-Endoperoxide Synthase 2(PTGS2), Jun Proto-Oncogene, AP-1 Transcription Factor Subunit(JUN), NAD(P)H Quinone Dehydrogenase 1(NQO1), Nitric Oxide Synthase 3(NOS3), and Leptin Receptor(LEPR), as potential therapeutic targets in myocardial infarction and for reducing adverse cardiovascular events (58). This evidence concerns the gene LEPR and myocardial infarction.