Similarly, the percentage of CD138+ EVs was significantly lower in HDs (5.13 ± 0.88%) compared to whole MM patients (10.30 ± 2.47%, p = 0.02) and subgroups NDMM (10.19 ± 2.2%, p = 0.01), and RRMM (22.35 ± 7.1%, p = 0.02), again without a significant difference between disease stages (Figure 2B). The gene discussed is SDC1; the disease is Miyoshi myopathy.